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Exercise and lifestyle intervention in chronic kidney disease: effects on cardiovascular function

D.HartR

10.1038/s41392-022-01090-z Signal Transduct Target Ther

The pharmacological actions of M6G [90] might be of particular relevance, as indicated by their high efficacy at MOP located in the locus coeruleus [111], where opioid-induced long-term neuronal inhibition is an important contributor to the development of tolerance [232, 233]